Thune to Run for Senate Minority Leader After GOP Midterm Losses

• Thune intends to run for Senate minority leader following the GOP's midterm defeat.
• Republicans lost at least five seats in the Senate during the midterm elections.
• Thune expressed Republicans' intent to oppose Democratic efforts to reverse Trump's policies.
• Thune's announcement came early Wednesday morning.
• The GOP's loss includes traditionally Republican-held seats.