Science2 sources
Spatial genomics tool maps DNA interactions, preserving cell locations
- A spatial genomics tool has been developed to map long-range DNA interactions.
- The tool preserves the locations of cells within tissues, aiding in understanding DNA's 3D organization.
- Previously, scientists had limited understanding of how DNA's 3D organization is regulated.
- DNA is packaged with proteins into chromatin, which is folded into complex 3D structures.
- This tool provides new insights into the regulation and changes of DNA's 3D organization over time.