Ionis Cuts Key Drug Revenue Forecast by 50%, Affecting Stock

• Ionis Pharmaceuticals announced a 50% reduction in its revenue forecast for a key drug.
• The company reported its third-quarter 2026 financial results, highlighting progress on key programs.
• The stock price of Ionis Pharmaceuticals dropped sharply following the announcement.
• The earnings call transcript was released on Monday, November 9, 2026.
• The company's stock price was reported to have fallen significantly by Barron's and Yahoo Finance.